乔治（詹姆斯•斯图尔特 James Stewart 饰）在圣诞节前准备自杀，这时上帝传来旨意，派天使拯救他，并让他了解到自己一生的使命——拯救那些不幸的人。乔治小时候左耳有疾，在贝德福德镇上的一家药店帮工。他很机灵，深得老板器重，同时也很招女孩喜欢。某日，老板接到爱子死亡的电报，悲痛欲绝，配错了药，幸亏乔治才化险为夷。乔治从小嫉恶如…

Beloved priest Father Thomasino is murdered in a San Francisco alley, and the police have few clues. But traffic cop Joe Martini becomes obsessed with finding the killer; he suspects Sylvio Malatesta. Ordered off the case, Joe turns in his badge and investigates alone. Soon he is a close friend of the Malatesta family,…